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Application note: Characterizing antibody aggregation with mass photometry
Learn how mass photometry can help assess changes in antibody behavior under various stress conditions. Discover how it can be used to analyze the fragmentation and aggregation of therapeutic antibodies in response to stressors like light, pH variations, and peroxide exposure. Find out the advantages automated mass photometry can offer, in terms of processing multiple samples with high reproducibility, across a wide mass range. Gain a deeper understanding of how mass photometry can support biopharmaceutical development and help ensure the quality and safety of monoclonal and bispecific antibodies.
Additional resources
BLOG: Overcoming analytical bottlenecks with mass photometry – with structural biologists from big pharma
Learn how mass photometry was used for the characterization of antibody and gene therapy samples at one of the top 5 pharmaceutical companies. Discover how the TwoMP Auto mass photometer helped biopharma experts overcome their experimental bottlenecks and how it compares with other bioanalytical methods.
WEBINAR: Monitoring aggregation levels of biosimilar mAbs using mass photometry and SEC
Learn how mass photometry compares with size-exclusion chromatography in measuring aggregation levels of monoclonal antibodies such as trastuzumab, and several trastuzumab biosimilars. Discover the pros and cons of each technology and the factors that should be considered when analyzing and comparing data generated by these different techniques.
