Protein and nucleic acid analytics with mass photometry

Whether they are focused on understanding vital cellular processes or developing new therapeutic antibodies, life scientists frequently need to perform biomolecular analytics – to analyze sample purity, measure binding affinities, quantify oligomerization and complex formation, and assess sample integrity. Mass photometry can do all this and more – by measuring the molecular mass of all biomolecules in a sample, individually, in solution.

Compatible with antibodies and other proteins, as well as membrane proteins and nucleic acids, mass photometry is a versatile tool for biomolecular analytics that helps life scientists understand exactly what is in their sample. It reveals the formation of complexes – between proteins, DNA or RNA – including oligomers, macromolecular assemblies and antibody/antigen binding. It can be used to estimate binding affinities, even for low-affinity interactions. Mass photometry can also be used to screen for sample sample degradation or aggregation, or for the presence of impurities.

With each measurement taking just a few minutes – requiring very little sample and minimal training – mass photometry puts the power of molecular mass measurement within easy reach. It enables researchers to focus on advancing their science.