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App note: Mass photometry with detergents

This application note will show you how to take and interpret mass photometry measurements of samples containing detergents. You will also learn how to perform quick dilutions prior to measurement to minimize detergent noise in your samples after membrane protein extraction. This application note reports the CMC values of common detergents as measured with mass photometry. It also shows data comparing soluble and aggregated protein samples to demonstrate how mass photometry can quickly evaluate membrane protein solubilization.

Cover app note detergents

Additional resources

WEBINAR​: Investigating membrane protein complexes with mass photometry

This webinar shows the applications of mass photometry for the study of two examples of macromolecular complexes formed by eukaryotic membrane proteins. In both cases, mass photometry supported the use of detergents for membrane protein extraction and solubilization. The webinar showcases what mass photometry can do, and what makes it suitable for studies of membrane protein complexes.

Additional resources​

BLOG POST​: How to study membrane proteins with mass photometry

Mass photometry provides valuable information on the purity and behavior of samples containing membrane proteins and membrane mimetics like detergents. In this blog post, we examine the role of mass photometry in membrane protein analysis and describe case studies that illustrate how mass photometry is contributing to the field.

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