Thank you for your interest in Refeyn’s mass photometry technology
Application note: Characterization of nanodisc-embedded membrane protein samples with mass photometry
In this application note you will see how mass photometry can be used to support membrane protein purification, and how it can measure and characterize samples of membrane proteins embedded in nanodiscs. You will read a real case study of mass photometry applied to the purification process of a membrane protein Aquaporin-4, solubilized with SMALPs.
Finally, you will see the results and interpretations of mass photometry analyses performed at different stages during the purification process – including size-exclusion chromatography (SEC) purification and antibody-based assays.
Additional resources
WEBINAR: Investigating membrane protein complexes with mass photometry
This webinar shows the applications of mass photometry for the study of two examples of macromolecular complexes formed by eukaryotic membrane proteins. In both cases, mass photometry was crucial to addressing highly relevant physiological questions. The webinar showcases what value can mass photometry deliver, and what makes it suitable for studies of membrane protein complexes.
BLOG: How to study membrane proteins with mass photometry
Mass photometry provides valuable information on the purity and behavior of samples containing membrane proteins and membrane mimetics. In this blog post, we examine the role of mass photometry in membrane protein analysis and describe case studies that illustrate how mass photometry is contributing to the field.
