Application Area: Interaction/Binding

Future Prospects for Biomolecular Trapping with Nanostructured Metals

Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer

Identification of a novel, tunable interface in the S.pombe HP1 protein, Swi6, that underpins epigenetic inheritance

Cryo-Electron Microscopy and Mass Analysis of Oligolysine-Coated DNA Nanostructures

High ionic strength dissociation assay reduces dimeric target interference in immunogenicity testing

Conserved Roles for the Dynein Intermediate Chain and Ndel1 in Assembly and Activation of Dynein

Multi-monoubiquitination controls VASP-mediated actin dynamics

Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus

Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA

Cooperativity and induced oligomerisation control the interaction of SARS-CoV-2 with its cellular receptor and patient-derived antibodies