Application Area: Structural Biology

The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity

Local environment in biomolecular condensates modulates enzymatic activity across length scales

Structural basis of host protein hijacking in human T-cell leukemia virus integration

Structure and function of Semaphorin-5A glycosaminoglycan interactions

VCF1 is an unconventional p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

Molecular insights into the maturation of phosphodiesterase 6 by the specialized chaperone complex of HSP90 with AIPL1

Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system

Conformational variability of cyanobacterial ChlI, the AAA+ motor of magnesium chelatase involved in chlorophyll biosynthesis

In vitro reconstitution reveals membrane clustering and double-stranded RNA recruitment by the enteroviral AAA+ ATPase 2C

Phage T3 overcomes the BREX defense through SAM cleavage and inhibition of SAM synthesis by SAM lyase