Biomolecule Type: Proteins

Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism

Polymerization of Bacillus subtilis MreB on a lipid membrane reveals lateral co-polymerization of MreB paralogs and strong effects of cations on filament formation

Homologous chromosomes are stably conjoined for Drosophila male meiosis I by SUM, a multimerized protein assembly with modules for DNA-binding and for separase-mediated dissociation co-opted from cohesin

Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases

Toxin-mediated depletion of nicotinamide dinucleotides drives persister formation in a human pathogen

Denaturing mass photometry for straightforward optimization of protein-protein cross-linking reactions at single-molecule level

Human hnRNPA1 reorganizes telomere-bound Replication Protein A

An atlas of protein homo-oligomerization across domains of life

Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements

Biophysical tools to study the oligomerization dynamics of Prx1-class peroxiredoxins