Molecular-scale biophysics focuses on the architecture, dynamics and interactions of the molecules of life: proteins, DNA, RNA, polysaccharides, lipids, by measuring their physical properties. It is fundamental to our understanding of how living organisms function, and for our ability to manipulate the function of these molecules, notably for therapeutic purposes. MOSBRI aims to address the urgent need for a truly integrated and multi-method approach to modern biophysics. To this end, MOSBRI conferences are central to the exchange of ideas and technological approaches by experts in various fields of biophysics.