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Tech note: Antibody aggregation analysis: Mass photometry vs. SEC-UV

Learn how mass photometry and SEC-UV compare and how they can both offer valuable insights into protein sample analysis through two case studies: By RIC biologics (Kortrijk, Belgium) and the University of Oxford’s Kavli Institute for Nanoscience Discovery.

Tech note SEC UV

Additional resources

APPLICATION NOTE ​: Characterization of forced antibody degradation with automated mass photometry

Learn how mass photometry can help assess changes in antibody behavior under various stress conditions. Discover how it can be used to analyze the fragmentation and aggregation of therapeutic antibodies in response to stressors like light, pH variations, and peroxide exposure. Find out the advantages automated mass photometry can offer, in terms of processing multiple samples with high reproducibility, across a wide mass range. 

APPLICATION NOTE : Characterization of protein interaction equilibria

Discover how mass photometry was used to study the oligomerization process of a recombinant protein that forms tetramers. Using this multimeric protein as an example, you can see how scientists measured the relative abundances of each oligomeric species across a range of physiologically relevant protein concentrations and assessed the effect of environmental factors (such as temperature) on reaction equilibria.  

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