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Tech note: Quantifying antibody aggregation with the mass photometry Antibody Stability Module
In this technical note, you will see how to use mass photometry and the Antibody Stability Module to quickly detect and quantify antibody aggregation. The tech note also shows how mass photometry can measure antibody aggregation at both nanomolar and micromolar concentrations.
To demonstrate the application of mass photometry measurements, this tech note shows measurements of commercial antibody samples, as well as the results of a forced degradation study.
Additional resources
TECH NOTE: Mass photometry vs. SEC in forced degradation studies
This tech note shows how mass photometry and SEC-UV compare when used to characterize the results of forced antibody degradation studies. We demonstrate sample analysis through two case studies: By RIC biologics (Kortrijk, Belgium) and the University of Oxford’s Kavli Institute for Nanoscience Discovery.
WEBINAR​: Rapid analytical approach for biologics characterization
In this webinar you will learn – via example data and case studies – how mass photometry supports the development and production of therapeutic biologics such as antibodies and AAVs. Mass photometry is a powerful bioanalytical tool that characterizes samples at the single-molecule level with low sample consumption, fast turnaround times and no need for labels. These strengths make mass photometry an ideal technique to characterize key analytical attributes of therapeutic biologics at different stages of development and production.
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