Application Area: Interaction/Binding

Quantifying the monomer-dimer equilibrium of tubulin with mass photometry

Validation of the binding stoichiometry between HCN channels and their neuronal regulator TRIP8b by single molecule measurements

The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation

The suppressor of copper sensitivity protein C from Caulobacter crescentus is a trimeric di­sulfide isomerase that binds copper(I) with subpicomolar affinity

The structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers

Assembly reactions of SARS-CoV-2 nucleocapsid protein with nucleic acid

Antibody–peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins

Structure of RADX and mechanism for regulation of RAD51 nucleofilaments

SMC motor proteins extrude DNA asymmetrically and contain a direction switch

The Human RNA Helicase DDX21 Presents a Dimerization Interface Necessary for Helicase Activity