Application Area: Oligomerization

Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor

The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP

Redox-dependent formation of a viral amyloid and functional impact

Small molecule nitroalkenes inhibit RAD51-mediated homologous recombination and amplify triple-negative breast cancer cell killing by DNA-directed therapies

Structural basis for guide RNA selection by the RESC1-RESC2 complex

Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders

The FHA domain is essential for the autoinhibition of KIF1A/UNC-104

Extracellular endosulfatase Sulf-2 harbors a chondroitin/dermatan sulfate chain that modulates its enzyme activity

Probing differences among Aβ oligomers with two triangular trimers derived from Aβ

Revealing Advanced Glycation End Products Associated Structural Changes in Serum Albumin