Application Area: Oligomerization

Mre11-Rad50 oligomerization promotes DNA double-strand break repair

Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex

Single-molecule fluorescence-based approach reveals novel mechanistic insights into human small heat shock protein chaperone function

Short oligomers rather than rings of human RAD52 promote single-strand annealing

Biophysical tools to study the oligomerization dynamics of Prx1-class peroxiredoxins

An atlas of protein homo-oligomerization across domains of life

Structures of the HER2–HER3–NRG1β complex reveal a dynamic dimer interface

Structure of dynein–dynactin on microtubules shows tandem adaptor binding

Discovery of a novel lactate dehydrogenase tetramerization domain using epitope mapping and peptides

The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells