Application Area: Structural Biology

A Multiscale approach reveals the molecular architecture of the autoinhibited kinesin KIF5A

The cryo-EM structure of the BoNT/Wo-NTNH complex reveals two immunoglobulin-like domains

Cryo-EM structure of DDM1-HELLS chimera bound to nucleosome reveals a mechanism of chromatin remodeling and disease regulation

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

Structural and biochemical investigations of a HEAT-repeat protein involved in the cytosolic iron-sulfur cluster assembly pathway

Molecular model of a bacterial flagellar motorin situreveals a “parts-list” of protein adaptations to increase torque

Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1

Cryo-EM structure of the cytosolic AhR complex

The structural mechanism of dimeric DONSON in replicative helicase activation

Structural characterization of the Sel1-like repeat protein LceB fromLegionella pneumophila