Application Area: Structural Biology

Structure of the extracellular region of the adhesion GPCR CELSR1 reveals a compact module which regulates G protein-coupling

Degron-mediated proteolysis of CrhR-like DEAD-box RNA helicases in cyanobacteria

The chromokinesin Kid forms a homodimer and moves processively along microtubules

The structural mechanism of dimeric DONSON in replicative helicase activation

Ηigh-resolution structure of mammalian PI31–20S proteasome complex reveals mechanism of proteasome inhibition

Architecture and infection-sensing mechanism of the bacterial PARIS defense system

Shape-Morphing of an Artificial Protein Cage with Unusual Geometry Induced by a Single Amino Acid Change

Sequential conformational transition of ArnB, an archaeal ortholog with Sec23/Sec24 core motif

Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases

Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements