Webinar | Are Your AAVs Filled? Determine Rapidly with Mass Photometry

In this webinar, our Product Manager Svea Cheeseman will provide insight into a novel mass photometry instrument tailored to address the challenges of AAV characterization. Moreover, we will see data proving its ability to reliably quantify the empty-full particle ratio for different AAV serotypes and at different purification levels, including benchmark data comparing the mass […]

Webinar | Probing Antibody Binding to the SARS-CoV-2 Spike Protein

Characterizing the mass of proteins and their complexes has a wide range of applications. However, the large degree of heterogeneity present in some biological systems have historically posed a near-unsurmountable challenge to traditional native mass spectrometry and classic structural biology techniques. To overcome this, researchers are turning to new, single-particle mass analysis methods. In this […]

Webinar | Quantifying Protein-Protein Interactions by Molecular Counting with Mass Photometry

Dr Grzegorz Piszczek (Director of the Biophysics Core Facility, NIH) and Fabian Soltermann (PhD candidate, Oxford University) discuss how mass photometry can be used to characterise and determine the purity, stoichiometry, binding affinity and kinetics of multi-protein interactions. They also cover a recent application of mass photometry: quantifying interactions of antibodies with Fc-receptors.

Webinar | Applications of Mass Photometry

In this webinar, Refeyn co-founder Prof. Justin Benesch discusses examples of mass photometry measurements for large protein complexes and draws comparisons with mass measurements obtained from native mass spectrometry and other techniques. Dr Nikolas Hundt also describes the use of mass photometry to visualise the nucleation process of actin filaments in real time.

Webinar | Measuring the heterogeneity of macromolecular machines by mass photometry

In this webinar, Dr Adar Sonn-Segev presents how mass photometry provides quantitative information on sample heterogeneity using minimal volumes with molecular resolution. She also discusses how this approach applies to several different workflows including chemical crosslinking and multi-step purification, comparing it to the standard tools for measuring sample purity.

Webinar | Measuring Membrane Proteins with Mass-Sensitive Particle Tracking

In this webinar, Dr Nikolas Hundt (Ludwigs-Maximilian-University Munich), describes a new mass photometry strategy for unlabelled molecules diffusing on supported lipid bilayers. With this approach, called mass-sensitive particle tracking (MSPT), researchers can determine the mass distributions and diffusion characteristics of membrane-associated protein complexes and observe protein assembly dynamics on a lipid interface in real time.

Webinar | How to Weigh Molecules with Light

In this webinar, featuring our co-founder and director Prof. Philipp Kukura discusses how mass photometry offers a universal way to study biomolecules, as well as its strengths and limitations.