BioProcess International Europe

BPI EU

Get exclusive access to the world’s leading bioprocessing experts, groundbreaking discoveries, and industry-defining collaborations. Join us in Hamburg and be part of something extraordinary.

8th Annual Bioprocessing International Summit Europe

Bioprocessing International Summit Europe

Bioprocessing Summit Europe brings together 750+ upstream, downstream, bioproduction, and analytical professionals from industry and academia to advance the manufacture, quality, and control of next generation biologics and genetic therapies. This 3-day, 14-track meeting has quickly become a premier event in the European bioprocessing calendar and focuses on the latest innovations in bioprocess R&D as […]

Advanced Therapies Congress

Advanced Therapies

The Advanced Therapies Congress is Europe’s largest commercial cell and gene therapy conference and exhibition. The event is for the leaders of pioneering ATMP companies and their most senior executives in charge of the latest tech and strategies that are driving the industry forward. With 10 tracks of content, the agenda covers everything from manufacturing, […]

NextGen Biomed

NextGen Biomed

NextGen Biomed is the biologics drug discovery & development meeting point — uniting six longstanding industry communities on one platform. More than 30,000 biologics and therapeutic R&D experts are enabled to build partnerships, align specialisms, bridge unknowns and commercially convert novel cures into life-changing outcomes for patients.

Innovative Upstream Process Analytical Technologies for Enhanced AAV Manufacturing

Adeno-associated viruses (AAVs) play a crucial role in gene therapy, but producing high-quality vectors at scale remains challenging, particularly due to inefficiencies in DNA packaging. This results in a high proportion of empty or improperly loaded capsids. To address this, Refeyn, Rentschler Biopharma, and the Cell and Gene Therapy Catapult, with support from Innovate UK, […]

De Novo Design of Allosterically Switchable Protein Assemblies

Designing nanodevices that can change shape and function in response to molecular signals is a key objective in protein design, paving the way for the development of switchable nanomaterials, triggerable drug-delivery systems, and molecular motors. In this talk, I will present recent progress in designing and characterizing a diverse range of switchable protein assemblies.

Evaluating Analytical Strategies to Quantify Capsid Titre: Towards a Platform-Method Approach to Accelerate AAV Drug Product Development

Traditional capsid titre methods rely on ELISA which commonly suffers from long turnaround times, low throughput, and large volume sample requirements. This limits the application of ELISA-based methods to routine analysis, thus requiring development of alternative high-throughput (HTP) capsid titre methods. We have performed a comprehensive assessment on currently available orthogonal capsid titre methods using […]

Teach Me in 10: Accelerating Cell and Gene Therapy Development

In this 10-minute session, we’ll show you how mass photometry is transforming AAV production with fast, reproducible measurements that use minimal sample at less than $5 per measurement. Mass photometry is also highly user-friendly, with a benchtop instrument that make it perfect for in-house use, cutting reliance on external facilities and boosting research efficiency without […]

Mass photometry to study the oligomerization of HACE1

Protein ubiquitination is a versatile post-translational modification that orchestrates many cellular pathways. Ubiquitin ligases are key specificity factors in this system. The HECT-type ubiquitin ligase HACE1 controls membrane dynamics and redox homeostasis by mechanisms that are still poorly understood at a structural level.