Enhancing cryo-EM workflows with mass photometry: A smarter pre-screening approach
Explore how mass photometry compares to traditional pre-screening tools—and how recent studies reveal its growing role and applications in pre-cryo-EM workflows. The impact of cryo-electron microscopy (cryo-EM) on structural biology has been transformational. Recognized with the Nobel Prize in Chemistry in 2017, cryo-EM has opened the door to atomic-level insights into some of the most […]
Mass photometry recognized by U.S. Pharmacopeia in new AAV reference standards for gene therapy quality
USP employs mass photometry as key orthogonal method for empty/full characterization of AAV capsids Refeyn’s SamuxMP mass photometer for AAV analytics – used for characterizing the U.S. Pharmacopeia’s new adeno-associated virus (AAV) reference standards. Oxford, UK (18 June, 2025) – Refeyn announces that mass photometry has been recognized by the U.S. Pharmacopeia (USP)—and referenced in […]
Refeyn Announces Leadership Transition: Jonathan Flint Steps Down as Chairman, Jean-Paul Mangeolle Appointed as Successor
Oxford, UK – 10 June 2025 – Refeyn, a leader in mass photometry and analytical instrumentation, today announced that Jonathan Flint is stepping down as Chairman of the Board of Directors after completing two successful three-year terms. Flint’s tenure has been marked by significant growth and innovation, and the company extends its deepest gratitude for his […]
New milestone: 500 mass photometers installed globally
Refeyn’s TwoMP mass photometer and MassFluidix HC system newly installed at the University of Copenhagen in action with Dr. Anni Kumari. Oxford, UK (07 May, 2025) – Refeyn, the company behind pioneering mass photometry technology, has announced the installation of the 500th system based on its novel single-particle bioanalytical technology – notably, within just seven […]
Revolutionizing AAV analytics with mass photometry
Mass photometry measures the mass of single particles in solution without disruptive preparation or labels. This powerful simplicity makes it a versatile technique, with a role to play in a variety of applications, from assessing antibody aggregation to measuring RNA length. Among these, characterizing AAVs is one where mass photometry really shines and is quickly […]
New Comprehensive Brochure: Bioanalytics with Mass Photometry
The new Refeyn brochure is your complete guide to mass photometry solutions and services. The brochure includes: A brief explanation of how mass photometry and macro mass photometry work An overview of key applications A description of the products and services available from Refeyn Whether you are new to mass photometry or want to refine […]
Using mass photometry to explore the evolution of carbon fixation
Form I Rubisco is one of the most abundant enzymes on Earth. It is responsible for assimilating atmospheric CO2 into organic matter, but how it obtained its high CO2 specificity is unknown.
Refeyn Expands into AAV-based Gene Therapy Manufacturing with GMP Software
The new SamuxMP software package for GMP empowers AAV manufacturing facilities with advanced process optimization capabilities
Using mass photometry to study compact CRISPR-Cas12f1 complexes
Due to its precise genome editing capabilities, the prokaryotic CRISPR–Cas system has revolutionized molecular biology – and has potential applications in gene therapy and biotechnology [1]. Nonetheless, recent research has highlighted the need for more compact CRISPR-Cas complexes, which could be delivered to cellular systems more efficiently [2]
Happy 500 (papers) to mass photometry!
There is no better measure for the success of an analytical technology than its widespread adoption by the people who need the best data! As news of the capabilities and applications of mass photometry spreads, more and more scientists are choosing to use it. In fact, the number of scientific publications relying on mass photometry has grown by an average of 168% per year over the past 6 years. In August 2024, we hit a new milestone: 500 mass photometry papers! For a technology as young as mass photometry, that is truly remarkable.
