Measuring viral vector purity, stability and physical titer in minutes – with just one tool
In this webinar, Dr. Laura Pala will discuss a new technology that enables fast, accurate and label-free analysis of adenovirus (AdV) and lentivirus (LV) samples for cell and gene therapy R&D. This technology – macro mass photometry – characterizes samples of large viral vectors in minutes, at a single-particle level. Dr. Pala will introduce the […]
Characterizing oligomerization dynamics of a ubiquitin ligase using mass photometry
This webcast will demonstrate harnessing the power of mass photometry to analyze the oligomeric state of the DCAF15–DDA1–DDB1 E3 ligase at low nanomolar concentrations. This study revealed, for the first time, the formation of dimers and trimers with quantified dissociation constants. The oligomeric remodelling effect emphasized the transition from trimer to monomer upon molecular glue […]
Mass photometry to study the oligomerization of HACE1
Protein ubiquitination is a versatile post-translational modification that orchestrates many cellular pathways. Ubiquitin ligases are key specificity factors in this system. The HECT-type ubiquitin ligase HACE1 controls membrane dynamics and redox homeostasis by mechanisms that are still poorly understood at a structural level.
Accelerating Protein Characterization with Mass Photometry
Join this webinar to learn why mass photometry is an essential technology in the analytical toolbox for the physio-chemical characterization of molecules in multipurpose facilities and labs.
Rapid Analytical Approach for Biologics Characterization – Mass Photometry
This webinar will also provide updates to the expanding portfolio of consumables and instrument add-ons. You will learn about MassFluidix HC, a microfluidic system which expands the concentration range amenable to mass photometry analysis to micromolar range. This new add-on offers rare insight into how proteins behave at high concentrations, hence allowing to study low […]
Rapidly Characterizing Complex Samples with Mass Photometry
In this webinar brought to you by Refeyn, Perla Vega and Philip Kitchen will discuss how to use mass photometry in protein purification workflows, sample characterization prior to cryo-electron microscopy analysis, and G-protein coupled receptor solubilization.
Advancing mAb Stability Studies With Mass Photometry
In this webinar, you’ll discover how mass photometry can be used for forced antibody degradation assessment, a crucial aspect of research and development for recombinant mAb therapeutics. Our expert speaker will also demonstrate how mass photometry data compares to and complements the current gold standard, size exclusion chromatography (SEC), as well as providing insights into […]
An Essential PAT Technology for Downstream Processing in AAV Manufacturing
This webinar aims to showcase the utility of mass photometry in characterizing AAV samples, providing crucial insights for downstream process development. The presentation will highlight the value of mass photometry for characterizing AAV samples during early process development and in accelerating optimization of the polishing step. The examples will demonstrate how mass photometry enables the […]
Advances in Cell and Gene Therapy: Characterizing Large Viral Vectors Using Macro Mass Photometry
In this GEN webinar, Dr. Laura Pala will discuss how macro mass photometry enables fast, qualitative analysis of adenovirus and lentivirus samples for cell and gene therapies. She will introduce KaritroMP, a novel analytical instrument that uses macro mass photometry to characterize large viral vectors in research and development environments. During the webinar, she will […]
Tau protein aggregation & neurodegenerative disease
Join this webinar to discover how a single-molecule technology mass photometry has played a role in the understanding of tau protein aggregation, which is involved in neurodegenerative diseases like Alzheimer’s and Parkinson’s. Learn about the coexistence of native and misfolded conformers and their impact on aggregation kinetics, unlocking new insights into tau aggregation mechanisms. Attend […]
