De Novo Design of Allosterically Switchable Protein Assemblies
Designing nanodevices that can change shape and function in response to molecular signals is a key objective in protein design, paving the way for the development of switchable nanomaterials, triggerable […]
Evaluating Analytical Strategies to Quantify Capsid Titre: Towards a Platform-Method Approach to Accelerate AAV Drug Product Development
Traditional capsid titre methods rely on ELISA which commonly suffers from long turnaround times, low throughput, and large volume sample requirements. This limits the application of ELISA-based methods to routine […]
Teach Me in 10: Accelerating Cell and Gene Therapy Development
In this 10-minute session, we’ll show you how mass photometry is transforming AAV production with fast, reproducible measurements that use minimal sample at less than $5 per measurement. Mass photometry […]
Leveraging mass photometry for efficient, precise, and rapid adeno-associated virus (AAV) empty:full quantification
This webinar is the second in a series covering our Challenge Themes and the collaborative research projects that are helping us to identify effective solutions to the challenges facing the […]
Quickly and accurately measure key analytical attributes of viral vectors with macro mass photometry
In this webinar, Dr. Laura Pala explains how the Karitro MP macro mass photometer measures the size and contrast (related to mass) of viral vectors at the single-particle level, enabling […]
Using Mass Photometry To Power Up the Development of AAV-Based Therapeutics
In this webinar, hear how mass photometry, an easy-to-use bioanalytical technology, can characterize AAV samples in minutes and using little sample. Our expert speaker will also discuss how mass photometry […]
Measuring viral vector purity, stability and physical titer in minutes – with just one tool
In this webinar, Dr. Laura Pala will discuss a new technology that enables fast, accurate and label-free analysis of adenovirus (AdV) and lentivirus (LV) samples for cell and gene therapy […]
Characterizing oligomerization dynamics of a ubiquitin ligase using mass photometry
This webcast will demonstrate harnessing the power of mass photometry to analyze the oligomeric state of the DCAF15–DDA1–DDB1 E3 ligase at low nanomolar concentrations. This study revealed, for the first […]
Mass photometry to study the oligomerization of HACE1
Protein ubiquitination is a versatile post-translational modification that orchestrates many cellular pathways. Ubiquitin ligases are key specificity factors in this system. The HECT-type ubiquitin ligase HACE1 controls membrane dynamics and […]
Accelerating Protein Characterization with Mass Photometry
Join this webinar to learn why mass photometry is an essential technology in the analytical toolbox for the physio-chemical characterization of molecules in multipurpose facilities and labs.