This webinar explores the latest advancements and persistent challenges in AAV-based gene therapy, focusing on analytical testing and manufacturing control. Dr. Anthony Blaszczyk introduces the first USP AAV reference materials, developed to support consistent testing across the gene therapy lifecycle – from raw material qualification to product release. Additionally, Drs. Paul Getty and Lauren Tomlinson present Pharmaron’s innovative use of mass photometry for rapid process development and in-process controls in large-scale AAV production, comparing it with other analytical techniques.