Application Area: Structural Biology

Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins

A bacterial tungsten-containing aldehyde oxidoreductase forms an enzymatic decorated protein nanowire

Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation

Structural Flexibility and Disassembly Kinetics of Single Ferritins Using Optical Nanotweezers

Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1

Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy

Mechanism of regulation of the Helicobacter pylori Cagβ ATPase by CagZ

Sequential conformational transition of ArnB, an archaeal ortholog with Sec23/Sec24 core motif

Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages

Allosteric activation of VCP, a AAA unfoldase, by small molecule mimicry