Everything you need to know about analysing AAVs with mass photometry
Ask any AAV researcher – figuring out how many of your capsids are filled and how many are empty is a long and laborious process. There is a clear need to overcome the drawbacks of the current gold-standard analytical methods so users can rapidly and cost-effectively characterise AAVs.
Analyzing complex SARS-CoV-2 samples with mass photometry
The SARS-CoV-2 pandemic has altered our lives and shaped the course of scientific research, bringing an explosion in studies on the virus. Mass photometry has proved valuable in coronavirus research, especially in characterising complex and heterogeneous proteins, and in analysing protein interactions and stoichiometry. In this blog post, we highlight ways that mass photometry has helped investigate previously intractable questions and advance our understanding of SARS-CoV-2.
Making sense of mass photometry measurements
Mass photometry is a novel way to measure the mass of biomolecules. It works by quantifying the light scattered by an individual molecule in solution, which is directly proportional to the molecule’s mass [1], [2] (read more about how mass photometry works).
Understanding the strengths and boundaries of mass photometry
Mass photometry is an analytical method that measures molecular mass by quantifying light scattering from individual biomolecules in solution [1]. When considering mass photometry as a new technology for your lab, it is important to understand whether it is suitable for the types of samples you need to analyze.
Here, we describe mass photometry’s mass range, resolution and experimental error, the concentration ranges that can be analyzed, and other information you will find useful as you explore mass photometry.
How does mass photometry work?
Mass photometry is a novel bioanalytical technology that measures molecular mass by quantifying light scattering from individual biomolecules in solution
