The presence of impurities—empty and partially filled capsids, often in large quantities—is one of the main challenges in AAV production. Quantifying the ratio of empty, partially filled, full, and overfull AAV capsids remains difficult with traditional methods. 

Mass photometry offers an easy-to-use solution that measures the empty-to-full AAV capsid ratio within minutes, using minimal sample amounts and requiring no sample preparation. Avoiding the need for large capital investments and highly skilled operators, it can be implemented across all stages of development and manufacturing. 

In this webinar, Katherine Lindsay, Product Manager for GMP at Refeyn, will share practical strategies for using Refeyn’s Samux™ product line to overcome common challenges in AAV characterization. She’ll discuss how this mass photometry solution supports robust capsid ratio analysis across all stages of development—from R&D through to GMP-regulated environments.