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App note: Quantifying adenovirus packaging with macro mass photometry
This application note – created in collaboration with the Jenner Institute at the University of Oxford – shows how macro mass photometry can be used to quickly evaluate critical quality attributes of adenoviral vector samples, such as purity or adenovirus packaging. It also shows that macro mass photometry can distinguish adenoviral vectors from helper virus populations. In this application note, macro mass photometry results are compared to expected values as well as to results from orthogonal techniques, including AUC and negative stain electron microscopy (nsEM).
Additional resources
WEBINAR: Characterizing large viral vectors using macro mass photometry
Accurate characterization of large viral vectors is a critical step in the development of viral vector-based gene therapies and vaccines. This webinar presents case studies and benchmark results on how the KaritroMP employs macro mass photometry to facilitate fast, straightforward, and qualitative analysis of single viral particles in cell and gene therapy applications. It also shows that it is well-suited for comparing different production and purification methods, as well as assessing batch-to-batch variations – ensuring the safety and efficacy of pharmaceutical products brought to market.
Macro mass photometry: A new way to characterize large viral vectors
Macro mass photometry is a revolutionary new technology for analyzing large viral vectors, such as adenoviruses (AdV) and lentiviruses (LVV). Returning results in minutes, it offers fast, simple, qualitative analysis to inform process development and optimization in the development of cell and gene therapies and vaccines. Here, you can learn the basic principles of macro mass photometry and its applications.
