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Application note: Mass Photometry on SARS-CoV-2

Learn how mass photometry can be used to study the mechanism by which the SARS-CoV-2 spike protein binds to the ACE2 receptor. Discover how you can measure the oligomeric state of the spike protein, its interaction with ACE2, and the conformation of the receptor-binding domain – gaining a better understanding of the virus entry process. 

Cover of app note SARS-CoV-2​

Additional resources

WEBINAR​: Probing Antibody Binding to the SARS-CoV-2 Spike Protein​

In this webinar, Dr. Victor Yin, a postdoctoral researcher of biomolecular mass spectrometry and proteomics at Utrecht University, will discuss how mass photometry and charge detection mass spectrometry enable the study of several challenging protein systems, including the interaction of full antibodies with SARS-CoV-2.

BLOG POST​: SARS-CoV-2 studies highlight mass photometry’s ability to characterise complex heterogeneous systems​

Mass photometry has proved valuable in coronavirus research, especially in characterising complex and heterogeneous proteins, and in analysing protein interactions and stoichiometry. In this blog post, we highlight ways that mass photometry has helped investigate previously intractable questions and advance our understanding of SARS-CoV-2. 

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