In cell and gene therapy manufacturing, increasing AAV complexity—featuring mixed populations of empty, partial, full, and aggregated capsids—has exposed the limits of traditional bulk analytical methods. These approaches can mask critical quality attributes and delay decision-making, increasing operational risk. 

In this GEN webinar, Ray Zhang (Franklin Biolabs) explores how mass photometry (MP) enables rapid, single-particle analysis to overcome these challenges. Learn how MP directly quantifies capsid species in native conditions, delivering faster, high-confidence insights. The session highlights strong agreement with SV AUC, providing valuable orthogonal validation while significantly reducing turnaround times. 

Discover how MP supports applications across the workflow, from in-process monitoring to impurity and aggregation analysis, and as a critical quality gate before fill-finish. Real-world case studies demonstrate improved troubleshooting, efficiency, and cost savings.