ON-DEMAND WEBINAR
Hear from our presenter Prof. Dr. Albert J. R. Heck and discover how he is using mass photometry
Versatility of mass photometry for the structural characterization of biomolecular assemblies present in blood
This webinar, on higher-order protein assemblies in our blood, showcases mass photometry’s ability to mass-analyze co-occurring assemblies.
It describes how mass photometry data improved models for C4b-binding protein (C4BP) macromolecular assembly and provided valuable insights about how multivalency in antibody therapeutics can be exploited to optimize antibacterial biotherapeutics.
More generally, the webinar shows how mass photometry complements other techniques in structural biology, such as (glyco)proteomics, cross-linking mass spectrometry (MS), native MS, computational modelling and single-molecule MS.
Presenter: Prof. Dr. Albert J.R. Heck
Chair, Biomolecular Mass Spectrometry and Proteomics
Utrecht University, The Netherlands
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Albert Heck is a distinguished Faculty Professor at Utrecht University in the Netherlands, and an expert in protein mass spectrometry (MS). He is a recognized pioneer in native and cross-linking MS. The Heck laboratory applies MS to problems in proteomics, phosphoproteomics, glycoproteomics, and structural biology – developing new mass spectrometers for studies on the structure and dynamics of, for instance, immune complexes, plasma glycoproteins and viruses.
Heck has received prestigious awards, including the American Chemical Society’s Frank H. Field and Joe L. Franklin Award (2015), the Dutch Research Council’s Spinoza Award (2017), the IMSC Thomson Award (2018), the Federation of European Biochemical Societies’ Krebs Medal (2018), and the Mendel Medal (2024). He is an elected member of the Dutch Royal Academy of Science and Art (KNAW) and EMBO.