Stopping bad samples at the door: Mass photometry for cryo‑EM success
Presenters:
Dr. Mathias Gschell, Head of Cryo-EM, BIMOVIS GmbH
Dr. Salma Jalal, Market Development Manager, Refeyn
Control sample heterogeneity with mass photometry
Achieving high-quality structural data starts with one critical factor: Sample quality.
Yet, controlling heterogeneity remains one of the biggest challenges in structure determination workflows. Traditional analytical methods are often time-consuming, expensive, or require large sample volumes – and fail to deliver the resolution needed for confident decisions.
In this on-demand webinar, discover how mass photometry is transforming sample analysis, offering a rapid, low-sample solution that outperforms conventional approaches like SEC. We also introduce MyMass™, a next-generation mass photometer designed for fast, reliable sample characterization – enabling researchers to assess sample quality in minutes and make better decisions before moving into complex workflows such as cryo-EM, native MS, SPR, or BLI.
What You’ll Learn
- Why sample preparation is often underestimated – though it may seem simple, it has the greatest impact on experimental success
- How mass photometry delivers superior resolution and sensitivity compared to traditional methods
- How to quickly assess sample heterogeneity, size distribution, and purity in solution
- Why mass photometry is a powerful complement to SEC and other biophysical techniques
- How to improve decision-making before investing in downstream workflows like cryo-EM, native MS, SPR, or BLI