Application Area: Interaction/Binding

Small-molecule screening of ribonuclease L binders for RNA degradation

Ribosome association primes the stringent factor Rel for tRNA-dependent locking in the A-site and activation of (p)ppGpp synthesis

Comparative Analysis of Antibodies and Heavily Glycosylated Macromolecular Immune Complexes by Size-Exclusion Chromatography Multi-Angle Light Scattering, Native Charge Detection Mass Spectrometry, and Mass Photometry

Therapeutic disruption of RAD52–ssDNA complexation via novel drug-like inhibitors

Mass-Sensitive Particle Tracking to Characterize Membrane-Associated Macromolecule Dynamics

Antiviral activity of bacterial TIR domains via immune signalling molecules.

Characterisation of the SUF FeS cluster machinery in the amitochondriate eukaryote Monocercomonoides exilis

A paradigm for regulation at the effector interface with RNA-binding proteins

Identification of a small-molecule inhibitor that selectively blocks DNA-binding by Trypanosoma brucei replication protein A1

Shelterin is a dimeric complex with extensive structural heterogeneity