Accelerating
  • discovery
  • basic research
  • drug development
  • manufacturing
through innovation

Mass photometry handbook
A handbook for all
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Mass Photometry User Group Meetings 2025!
Four user group meetings scheduled across Europe and North America, register today!
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Mass Photometry Workshop
Johannesburg 7th - 8th July & Cape Town 10th -11th July
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Handbook – Mass photometry for advanced therapies
Handbook – Mass photometry for advanced therapies Exploring the utility of mass photometry for characterization of adeno-associated virus (AAV) and adenovirus (AdV) based therapeutics
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New Blog: New milestone: 500 mass photometers installed globally
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Starting on May 26th our consumables pricing will change, and our catalog will be adjusted to better meet your needs. These changes are based on your feedback from our survey earlier this year.

Thank you for helping us improve! 

Mass photometry. A bold approach.

Current bioanalytical techniques often employ binding, labeling, or separation methods to measure molecular mass, molecular interactions, and structural integrity, but these methods can alter the native state of the molecule, leading to inaccurate or incomplete characterization.

At Refeyn, we are challenging the status quo by leveraging the unique properties of mass photometry to directly measure molecular mass at the single molecule level in solution without the use of labels, simplifying sample preparation and capturing true molecular behaviour dynamics in a native, aqueous environment.

Characterize

  • Proteins
  • Nucleic Acids
  • Adeno-associated viruses (AAVs)
  • Adeno-viruses
  • Lenti-viruses
  • Virus Like Particles (VLPs)

Determine

  • Aggregation or Degradation
  • Capsid Loading
  • Molecular Interactions
  • Oligomeric State
  • Sample Heterogeneity​ and Purity
  • Stoichiometry

Empowering molecular discovery

From TwoMP to SamuxMP and KaritroMP, our mass photometers provide unparalleled precision and actionable insights.

TwoMP mass photometer
TwoMP

Measure molecular mass of biomolecules with speed, accuracy, and simplicity. Automated version available.

SamuxMP mass photometry instrument
SamuxMP

Rapidly analyze full, partial, and empty ratios for AAV development and manufacturing. Automated version available.

KaritroMP macro mass photometer
KaritroMP

Characterize larger viral or virus like particle vectors providing information on size, purity and stability within minutes.

Featured applications

Vector analytics

Accelerate process development and manufacturing with accurate, efficient AAV analytics.

Biomolecular analytics

Gain accurate insights into antibody-target interactions, aggregation, and fragmentation.

Transforming your research

"We're generating data to compare mass photometry with gold standards like AUC and cryoTEM. Early indications show that it’s much quicker and equally accurate. It's a game changer in AAV characterization, for us as well as our clients."

Mass photometry publications

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Our team

Our courageous, creative, and caring team strives each day to find high-quality, sustainable solutions that benefit our customers and society as a whole. Learn more about the cultural values driving our bold approach to innovation.

Let's get started! Contact us for more information and quotes on our products or to request service for your instrument. We’re here to help.