The MassFluidix HC – Sample Prep Kit is designed to streamline and enhance your mass photometry experiments by integrating fast sample dilution and measurement into a single workflow. Specifically developed for use with Refeyn’s MassFluidix HC accesory for mass photometry instruments, this kit enables precise data acquisition.
Each kit includes:
- 1 MassFluidix HC chip (supports 5 measurements per chip)
- 2 bags of mini luer connectors (10 connectors per bag)
- 1 box of lens cleaning tissues (25 sheets)
The MassFluidix HC chip is a microfluidic consumable that combines sample and dilution buffer using a reverse Tesla valve mixer, allowing for very fast dilution immediately prior to starting the experiment – less than 37 ms from the sample inlet to the observation area. Once mixed, the diluted sample flows through a defined observation area where the mass photometry measurement is performed. This workflow effectively increases the concentration range of Refeyn mass photometers up to 50 µM, enabling the analysis of low affinity interactions.
In high-concentration workflows, the MassFluidix HC system extends the power of mass photometry to samples up to 50 micromolar. It allows researchers to study protein-protein interactions, binding behaviour, and oligomerization dynamics in conditions closer to physiological relevance.
Please refer to page number 25 in the linked user manual for further details.